An unexpected coronavirus treatment update comes from the FDA, which has placed the emergency approval of blood plasma for COVID-19 on hold. Health experts, including Dr. Anthony Fauci, think the conclusions from a Mayo Clinic study that enrolled thousands of patients aren’t strong enough and need more scrutiny. The health
Mayo Clinic researchers reported a strong hint that blood plasma from COVID-19 survivors helps other patients recover, but it’s not proof and some experts worry if, amid clamor for the treatment, they’ll ever get a clear answer. The study involved over 35,000 patients that received convalescent plasma therapy. Those patients
The National Institutes of Health has announced that clinical trials of antibodies are now starting. These trials are to prevent infection instead of treating coronavirus infections. Two Phase 3, randomized, placebo-controlled, double-blind clinical trials testing whether experimental monoclonal antibodies (mAbs) can prevent infection by SARS-CoV-2 coronavirus are now enrolling healthy
Preliminary research by Mayo Clinic shows that high-dose plasma therapy is correlated with fewer deaths in patients with severe COVID-19. A 10 percentage point difference in deaths was found when comparing hospitalized COVID-19 patients who received donor plasma with high concentrations of virus-fighting antibodies compared with those who received lower
This week on Podcast-19, FiveThirtyEight talks about lab-grown antibodies, called monoclonal antibodies, that could temporarily protect people from COVID-19. How soon might they be available for the public? This podcast episode also discusses Dexamethasone, a steroid drug that appears promising for COVID-19 patients.
Hospitals are short on convalescent plasma, and there’s only one place they can find it. “We can’t purchase it; we can’t get it from anywhere except the community,” said Dr. Kirk Voelker, Sarasota Memorial Hospital’s critical care specialist. Supply of convalescent plasma is the primary limitation of its widespread use
Neutralizing monoclonal antibodies (mAbs) may be a highly effective way to treat and prevent COVID-19 while waiting for a vaccine. Watch this video to find out how these drugs are created and how they target the SARS-CoV-2 virus. JAMA presents an excellent overview of how monoclonal antibodies could be used